---
res:
  bibo_abstract:
  - <jats:title>Abstract</jats:title><jats:p>Exercise is described to provoke enhancements
    of cardiorespiratory fitness in persons with Multiple Sclerosis (pwMS). However,
    a high inter-individual variability in training responses has been observed. This
    analysis investigates response heterogeneity in cardiorespiratory fitness following
    high intensity interval (HIIT) and moderate continuous training (MCT) and analyzes
    potential predictors of cardiorespiratory training effects in pwMS. 131 pwMS performed
    HIIT or MCT 3–5x/ week on a cycle ergometer for three weeks. Individual responses
    were classified. Finally, a multiple linear regression was conducted to examine
    potential associations between changes of absolute peak oxygen consumption (absolute
    ∆V̇O2peak/kg), training modality and participant’s characteristics. Results show
    a time and interaction effect for ∆V̇O2peak/kg. Absolute changes of cardiorespiratory
    responses were larger and the non-response proportions smaller in HIIT vs. MCT.
    The model accounting for 8.6% of the variance of ∆V̇O2peak/kg suggests that HIIT,
    younger age and lower baseline fitness predict a higher absolute ∆V̇O2peak/kg
    following an exercise intervention. Thus, this work implements a novel approach
    that investigates potential determinants of cardiorespiratory response heterogeneity
    within a clinical setting and analyzes a remarkable bigger sample. Further predictors
    need to be identified to increase the knowledge about response heterogeneity,
    thereby supporting the development of individualized training recommendations
    for pwMS.</jats:p>@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Marit Lea
      foaf_name: Schlagheck, Marit Lea
      foaf_surname: Schlagheck
      foaf_workInfoHomepage: http://www.librecat.org/personId=117661
    orcid: '0000-0002-8913-6080 '
  - foaf_Person:
      foaf_givenName: Anika
      foaf_name: Wucherer, Anika
      foaf_surname: Wucherer
  - foaf_Person:
      foaf_givenName: Annette
      foaf_name: Rademacher, Annette
      foaf_surname: Rademacher
  - foaf_Person:
      foaf_givenName: Niklas
      foaf_name: Joisten, Niklas
      foaf_surname: Joisten
  - foaf_Person:
      foaf_givenName: Sebastian
      foaf_name: Proschinger, Sebastian
      foaf_surname: Proschinger
  - foaf_Person:
      foaf_givenName: David
      foaf_name: Walzik, David
      foaf_surname: Walzik
  - foaf_Person:
      foaf_givenName: Wilhelm
      foaf_name: Bloch, Wilhelm
      foaf_surname: Bloch
  - foaf_Person:
      foaf_givenName: Jan
      foaf_name: Kool, Jan
      foaf_surname: Kool
  - foaf_Person:
      foaf_givenName: Roman
      foaf_name: Gonzenbach, Roman
      foaf_surname: Gonzenbach
  - foaf_Person:
      foaf_givenName: Jens
      foaf_name: Bansi, Jens
      foaf_surname: Bansi
  - foaf_Person:
      foaf_givenName: Philipp
      foaf_name: Zimmer, Philipp
      foaf_surname: Zimmer
  bibo_doi: 10.1055/a-1481-8639
  bibo_issue: '14'
  bibo_volume: 42
  dct_date: 2021^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0172-4622
  - http://id.crossref.org/issn/1439-3964
  dct_language: eng
  dct_publisher: Georg Thieme Verlag KG@
  dct_title: 'VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To
    HIIT or Not to HIIT?@'
...