{"citation":{"bibtex":"@article{Höfler_Limprasart_Rösler_Fleckenstein_Brodrecht_Herr_Schäfer_Biesalski_Breitzke_Gutmann_2023, title={Fluorine-Labeled N-Boc-l-proline as a Marker for Solid-State NMR Characterization of Biofunctionalizations on Paper Substrates}, volume={127}, number={7}, journal={Journal of Physical Chemistry C}, publisher={American Chemical Society}, author={Höfler, Mark V. and Limprasart, Waranya and Rösler, Lorenz and Fleckenstein, Max and Brodrecht, Martin and Herr, Kevin and Schäfer, Jan-Lukas and Biesalski, Markus and Breitzke, Hergen and Gutmann, Torsten}, year={2023}, pages={3570–3578} }","mla":"Höfler, Mark V., et al. “Fluorine-Labeled N-Boc-l-Proline as a Marker for Solid-State NMR Characterization of Biofunctionalizations on Paper Substrates.” <i>Journal of Physical Chemistry C</i>, vol. 127, no. 7, American Chemical Society, 2023, pp. 3570–3578.","short":"M.V. Höfler, W. Limprasart, L. Rösler, M. Fleckenstein, M. Brodrecht, K. Herr, J.-L. Schäfer, M. Biesalski, H. Breitzke, T. Gutmann, Journal of Physical Chemistry C 127 (2023) 3570–3578.","apa":"Höfler, M. V., Limprasart, W., Rösler, L., Fleckenstein, M., Brodrecht, M., Herr, K., Schäfer, J.-L., Biesalski, M., Breitzke, H., &#38; Gutmann, T. (2023). Fluorine-Labeled N-Boc-l-proline as a Marker for Solid-State NMR Characterization of Biofunctionalizations on Paper Substrates. <i>Journal of Physical Chemistry C</i>, <i>127</i>(7), 3570–3578.","chicago":"Höfler, Mark V., Waranya Limprasart, Lorenz Rösler, Max Fleckenstein, Martin Brodrecht, Kevin Herr, Jan-Lukas Schäfer, Markus Biesalski, Hergen Breitzke, and Torsten Gutmann. “Fluorine-Labeled N-Boc-l-Proline as a Marker for Solid-State NMR Characterization of Biofunctionalizations on Paper Substrates.” <i>Journal of Physical Chemistry C</i> 127, no. 7 (2023): 3570–3578.","ieee":"M. V. Höfler <i>et al.</i>, “Fluorine-Labeled N-Boc-l-proline as a Marker for Solid-State NMR Characterization of Biofunctionalizations on Paper Substrates,” <i>Journal of Physical Chemistry C</i>, vol. 127, no. 7, pp. 3570–3578, 2023.","ama":"Höfler MV, Limprasart W, Rösler L, et al. Fluorine-Labeled N-Boc-l-proline as a Marker for Solid-State NMR Characterization of Biofunctionalizations on Paper Substrates. <i>Journal of Physical Chemistry C</i>. 2023;127(7):3570–3578."},"intvolume":"       127","page":"3570–3578","year":"2023","issue":"7","publication_identifier":{"issn":["1932-7447"]},"title":"Fluorine-Labeled N-Boc-l-proline as a Marker for Solid-State NMR Characterization of Biofunctionalizations on Paper Substrates","author":[{"full_name":"Höfler, Mark V.","last_name":"Höfler","first_name":"Mark V."},{"last_name":"Limprasart","full_name":"Limprasart, Waranya","first_name":"Waranya"},{"full_name":"Rösler, Lorenz","last_name":"Rösler","first_name":"Lorenz"},{"full_name":"Fleckenstein, Max","last_name":"Fleckenstein","first_name":"Max"},{"first_name":"Martin","full_name":"Brodrecht, Martin","last_name":"Brodrecht"},{"first_name":"Kevin","full_name":"Herr, Kevin","last_name":"Herr"},{"first_name":"Jan-Lukas","full_name":"Schäfer, Jan-Lukas","last_name":"Schäfer"},{"first_name":"Markus","last_name":"Biesalski","full_name":"Biesalski, Markus"},{"first_name":"Hergen","last_name":"Breitzke","full_name":"Breitzke, Hergen"},{"first_name":"Torsten","last_name":"Gutmann","full_name":"Gutmann, Torsten","id":"118165"}],"date_created":"2026-02-07T15:46:14Z","volume":127,"date_updated":"2026-02-17T16:16:46Z","publisher":"American Chemical Society","status":"public","abstract":[{"text":"An efficient approach employing 4-dimethylaminopyridine and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride as the coupling reagent is presented, which enables the functionalization of cotton linter paper substrates with the 19F spin label N-boc-cis-4-fluoro-l-proline. This spin label can be easily quantified by 19F magic angle spinning (MAS) NMR experiments to determine its loading on paper substrates. During the functionalization, the spin label stays intact, as confirmed by the 1H–19F heterocorrelation (1H → 19F CP MAS FSLG HETCOR) experiments. In combination with dynamic nuclear polarization (19F MAS DNP), the N-boc-cis-4-fluoro-l-proline spin label allows us to inspect 1 μmol/g and even lower molecule loadings on paper substrates, providing a highly sensitive local probe to analyze the structure of biofunctionalizations at the nanoscale on paper substrates in the future. An efficient approach employing 4-dimethylaminopyridine and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride as the coupling reagent is presented, which enables the functionalization of cotton linter paper substrates with the 19F spin label N-boc-cis-4-fluoro-l-proline. This spin label can be easily quantified by 19F magic angle spinning (MAS) NMR experiments to determine its loading on paper substrates. During the functionalization, the spin label stays intact, as confirmed by the 1H–19F heterocorrelation (1H → 19F CP MAS FSLG HETCOR) experiments. In combination with dynamic nuclear polarization (19F MAS DNP), the N-boc-cis-4-fluoro-l-proline spin label allows us to inspect 1 μmol/g and even lower molecule loadings on paper substrates, providing a highly sensitive local probe to analyze the structure of biofunctionalizations at the nanoscale on paper substrates in the future.","lang":"eng"}],"type":"journal_article","publication":"Journal of Physical Chemistry C","language":[{"iso":"eng"}],"extern":"1","user_id":"100715","_id":"63987"}