article published Katharina S. Weber author Sabrina Schlesinger author Alexander Lang author Janina Goletzke author Cara Övermöhle author Eike A. Strathmann author Klaus Straßburger author Nitika Singh author Oana-Patricia Zaharia author Sandra Trenkamp author Robert Wagner author Wolfgang Lieb author Anette Buyken author 65985 Michael Roden author Christian Herder author H. Al-Hasani author B. Belgardt author G.J. Bönhof author G. Geerling author A. Icks author K. Jandeleit-Dahm author O. Kuß author E. Lammert author S. Schlesinger author V. Schrauwen-Hinderling author J. Szendroedi author Sandra Trenkamp author 22 department <jats:title>Abstract</jats:title> <jats:p> Diet impacts cardiovascular disease risk, but the association across diabetes subtypes is unclear. We thus aimed to assess the association between dietary factors and estimated 10-year cardiovascular disease risk across diabetes subtypes in the German Diabetes Study (GDS). Participants with recent-onset diabetes and from the 5-year follow-up examination were combined (n=635, mean age 47.5±12.9 years, 60% male) and classified into diabetes subtypes. Subtypes with prevalence &gt;10% were included in cross-sectional analyses: severe autoimmune diabetes (39%), mild obesity-related diabetes (31%), and mild age-related diabetes (30%). Carbohydrate quality parameters and adherence to dietary patterns were assessed from food frequency questionnaires. Differences in associations between these dietary factors and 10-year cardiovascular risk estimated by SCORE2-Diabetes across subtypes were examined using multivariable-adjusted linear regression models including an interaction term. In people with severe autoimmune diabetes, the overall and the healthful plant-based diet index were associated with lower estimated 10-year cardiovascular risk (ß [95% CI] -6.8 [-12.1; -1.2] and -8.8% [-14.0; -3.2] per 1-standard deviation increases, respectively), while these associations were not evident among the remaining two subtypes (p-value for interaction between subtypes &lt;0.05). Our findings suggest subtype-specific associations of plant-based dietary patterns with estimated cardiovascular risk, warranting further research from longitudinal and intervention studies. <jats:bold>Trial registration:</jats:bold> Clinicaltrials.gov: NCT01055093 </jats:p> Springer Science and Business Media LLC2026 eng 2045-232210.1038/s41598-026-57026-y 161 Weber, Katharina S., et al. “Differential Associations of Dietary Patterns with Estimated 10-Year Cardiovascular Risk in Diabetes Subtypes.” <i>Scientific Reports</i>, vol. 16, no. 1, 20783, Springer Science and Business Media LLC, 2026, doi:<a href="https://doi.org/10.1038/s41598-026-57026-y">10.1038/s41598-026-57026-y</a>. @article{Weber_Schlesinger_Lang_Goletzke_Övermöhle_Strathmann_Straßburger_Singh_Zaharia_Trenkamp_et al._2026, title={Differential associations of dietary patterns with estimated 10-year cardiovascular risk in diabetes subtypes}, volume={16}, DOI={<a href="https://doi.org/10.1038/s41598-026-57026-y">10.1038/s41598-026-57026-y</a>}, number={120783}, journal={Scientific Reports}, publisher={Springer Science and Business Media LLC}, author={Weber, Katharina S. and Schlesinger, Sabrina and Lang, Alexander and Goletzke, Janina and Övermöhle, Cara and Strathmann, Eike A. and Straßburger, Klaus and Singh, Nitika and Zaharia, Oana-Patricia and Trenkamp, Sandra and et al.}, year={2026} } Weber KS, Schlesinger S, Lang A, et al. Differential associations of dietary patterns with estimated 10-year cardiovascular risk in diabetes subtypes. <i>Scientific Reports</i>. 2026;16(1). doi:<a href="https://doi.org/10.1038/s41598-026-57026-y">10.1038/s41598-026-57026-y</a> K. S. Weber <i>et al.</i>, “Differential associations of dietary patterns with estimated 10-year cardiovascular risk in diabetes subtypes,” <i>Scientific Reports</i>, vol. 16, no. 1, Art. no. 20783, 2026, doi: <a href="https://doi.org/10.1038/s41598-026-57026-y">10.1038/s41598-026-57026-y</a>. Weber, K. S., Schlesinger, S., Lang, A., Goletzke, J., Övermöhle, C., Strathmann, E. A., Straßburger, K., Singh, N., Zaharia, O.-P., Trenkamp, S., Wagner, R., Lieb, W., Buyken, A., Roden, M., Herder, C., Al-Hasani, H., Belgardt, B., Bönhof, G. J., Geerling, G., … Trenkamp, S. (2026). Differential associations of dietary patterns with estimated 10-year cardiovascular risk in diabetes subtypes. <i>Scientific Reports</i>, <i>16</i>(1), Article 20783. <a href="https://doi.org/10.1038/s41598-026-57026-y">https://doi.org/10.1038/s41598-026-57026-y</a> Weber, Katharina S., Sabrina Schlesinger, Alexander Lang, Janina Goletzke, Cara Övermöhle, Eike A. Strathmann, Klaus Straßburger, et al. “Differential Associations of Dietary Patterns with Estimated 10-Year Cardiovascular Risk in Diabetes Subtypes.” <i>Scientific Reports</i> 16, no. 1 (2026). <a href="https://doi.org/10.1038/s41598-026-57026-y">https://doi.org/10.1038/s41598-026-57026-y</a>. K.S. Weber, S. Schlesinger, A. Lang, J. Goletzke, C. Övermöhle, E.A. Strathmann, K. Straßburger, N. Singh, O.-P. Zaharia, S. Trenkamp, R. Wagner, W. Lieb, A. Buyken, M. Roden, C. Herder, H. Al-Hasani, B. Belgardt, G.J. Bönhof, G. Geerling, A. Icks, K. Jandeleit-Dahm, O. Kuß, E. Lammert, S. Schlesinger, V. Schrauwen-Hinderling, J. Szendroedi, S. Trenkamp, Scientific Reports 16 (2026). 672822026-09-30T10:22:02Z2026-09-30T10:23:54Z