Fast pH-mediated changes of the viscosity of protein solutions studied with a voltage-modulated quartz crystal microbalance

A. Gödde, C. Leppin, F.S. Meyer, A. Langhoff, J. Hartl, P. Garidel, D. Johannsmann, Biointerphases 15 (2020).

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Journal Article | Published | English
Author
Gödde, Alexander; Leppin, ChristianLibreCat; Meyer, Frederick S.; Langhoff, Arne; Hartl, Josef; Garidel, Patrick; Johannsmann, Diethelm
Abstract
<jats:p>An electrochemical quartz crystal microbalance is described, which achieves a time resolution down to 100 μs. Accumulation and averaging over a few hours bring the noise down to about 30 mHz. The application examples are pH-driven viscosity changes in albumin solutions. The pH was switched with the electrode potential. The characteristic response time is in the millisecond range. The focus is on experimental aspects as well as advantages and limitations of the technique.</jats:p>
Publishing Year
Journal Title
Biointerphases
Volume
15
Issue
2
Article Number
021004
LibreCat-ID

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Gödde A, Leppin C, Meyer FS, et al. Fast pH-mediated changes of the viscosity of protein solutions studied with a voltage-modulated quartz crystal microbalance. Biointerphases. 2020;15(2). doi:10.1116/1.5140619
Gödde, A., Leppin, C., Meyer, F. S., Langhoff, A., Hartl, J., Garidel, P., & Johannsmann, D. (2020). Fast pH-mediated changes of the viscosity of protein solutions studied with a voltage-modulated quartz crystal microbalance. Biointerphases, 15(2), Article 021004. https://doi.org/10.1116/1.5140619
@article{Gödde_Leppin_Meyer_Langhoff_Hartl_Garidel_Johannsmann_2020, title={Fast pH-mediated changes of the viscosity of protein solutions studied with a voltage-modulated quartz crystal microbalance}, volume={15}, DOI={10.1116/1.5140619}, number={2021004}, journal={Biointerphases}, publisher={American Vacuum Society}, author={Gödde, Alexander and Leppin, Christian and Meyer, Frederick S. and Langhoff, Arne and Hartl, Josef and Garidel, Patrick and Johannsmann, Diethelm}, year={2020} }
Gödde, Alexander, Christian Leppin, Frederick S. Meyer, Arne Langhoff, Josef Hartl, Patrick Garidel, and Diethelm Johannsmann. “Fast pH-Mediated Changes of the Viscosity of Protein Solutions Studied with a Voltage-Modulated Quartz Crystal Microbalance.” Biointerphases 15, no. 2 (2020). https://doi.org/10.1116/1.5140619.
A. Gödde et al., “Fast pH-mediated changes of the viscosity of protein solutions studied with a voltage-modulated quartz crystal microbalance,” Biointerphases, vol. 15, no. 2, Art. no. 021004, 2020, doi: 10.1116/1.5140619.
Gödde, Alexander, et al. “Fast pH-Mediated Changes of the Viscosity of Protein Solutions Studied with a Voltage-Modulated Quartz Crystal Microbalance.” Biointerphases, vol. 15, no. 2, 021004, American Vacuum Society, 2020, doi:10.1116/1.5140619.

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