Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation
S. Ramakrishnan, L. Schärfen, K. Hunold, S. Fricke, G. Grundmeier, M. Schlierf, A. Keller, G. Krainer, Nanoscale 11 (2019) 16270–16276.
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Journal Article
| Published
| English
Author
Ramakrishnan, Saminathan;
Schärfen, Leonard;
Hunold, Kristin;
Fricke, Sebastian;
Grundmeier, GuidoLibreCat;
Schlierf, Michael;
Keller, AdrianLibreCat 
;
Krainer, Georg
;
Krainer, GeorgDepartment
Abstract
<p>Merging of bridging staples with adjacent oligonucleotide sequences leads to a moderate increase of DNA origami stability, while enzymatic ligation after assembly yields a reinforced nanostructure with superior stability at up to 37 °C and in the presence of 6 M urea.</p>
Publishing Year
Journal Title
Nanoscale
Volume
11
Page
16270-16276
LibreCat-ID
Cite this
Ramakrishnan S, Schärfen L, Hunold K, et al. Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation. Nanoscale. 2019;11:16270-16276. doi:10.1039/c9nr04460d
Ramakrishnan, S., Schärfen, L., Hunold, K., Fricke, S., Grundmeier, G., Schlierf, M., … Krainer, G. (2019). Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation. Nanoscale, 11, 16270–16276. https://doi.org/10.1039/c9nr04460d
@article{Ramakrishnan_Schärfen_Hunold_Fricke_Grundmeier_Schlierf_Keller_Krainer_2019, title={Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation}, volume={11}, DOI={10.1039/c9nr04460d}, journal={Nanoscale}, author={Ramakrishnan, Saminathan and Schärfen, Leonard and Hunold, Kristin and Fricke, Sebastian and Grundmeier, Guido and Schlierf, Michael and Keller, Adrian and Krainer, Georg}, year={2019}, pages={16270–16276} }
Ramakrishnan, Saminathan, Leonard Schärfen, Kristin Hunold, Sebastian Fricke, Guido Grundmeier, Michael Schlierf, Adrian Keller, and Georg Krainer. “Enhancing the Stability of DNA Origami Nanostructures: Staple Strand Redesign versus Enzymatic Ligation.” Nanoscale 11 (2019): 16270–76. https://doi.org/10.1039/c9nr04460d.
S. Ramakrishnan et al., “Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation,” Nanoscale, vol. 11, pp. 16270–16276, 2019.
Ramakrishnan, Saminathan, et al. “Enhancing the Stability of DNA Origami Nanostructures: Staple Strand Redesign versus Enzymatic Ligation.” Nanoscale, vol. 11, 2019, pp. 16270–76, doi:10.1039/c9nr04460d.
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