VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT or Not to HIIT?

M.L. Schlagheck, A. Wucherer, A. Rademacher, N. Joisten, S. Proschinger, D. Walzik, W. Bloch, J. Kool, R. Gonzenbach, J. Bansi, P. Zimmer, International Journal of Sports Medicine 42 (2021) 1319–1328.

Download
No fulltext has been uploaded.
Journal Article | Published | English
Author
Schlagheck, Marit LeaLibreCat ; Wucherer, Anika; Rademacher, Annette; Joisten, Niklas; Proschinger, Sebastian; Walzik, David; Bloch, Wilhelm; Kool, Jan; Gonzenbach, Roman; Bansi, Jens; Zimmer, Philipp
Abstract
<jats:title>Abstract</jats:title><jats:p>Exercise is described to provoke enhancements of cardiorespiratory fitness in persons with Multiple Sclerosis (pwMS). However, a high inter-individual variability in training responses has been observed. This analysis investigates response heterogeneity in cardiorespiratory fitness following high intensity interval (HIIT) and moderate continuous training (MCT) and analyzes potential predictors of cardiorespiratory training effects in pwMS. 131 pwMS performed HIIT or MCT 3–5x/ week on a cycle ergometer for three weeks. Individual responses were classified. Finally, a multiple linear regression was conducted to examine potential associations between changes of absolute peak oxygen consumption (absolute ∆V̇O2peak/kg), training modality and participant’s characteristics. Results show a time and interaction effect for ∆V̇O2peak/kg. Absolute changes of cardiorespiratory responses were larger and the non-response proportions smaller in HIIT vs. MCT. The model accounting for 8.6% of the variance of ∆V̇O2peak/kg suggests that HIIT, younger age and lower baseline fitness predict a higher absolute ∆V̇O2peak/kg following an exercise intervention. Thus, this work implements a novel approach that investigates potential determinants of cardiorespiratory response heterogeneity within a clinical setting and analyzes a remarkable bigger sample. Further predictors need to be identified to increase the knowledge about response heterogeneity, thereby supporting the development of individualized training recommendations for pwMS.</jats:p>
Publishing Year
Journal Title
International Journal of Sports Medicine
Volume
42
Issue
14
Page
1319-1328
LibreCat-ID

Cite this

Schlagheck ML, Wucherer A, Rademacher A, et al. VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT or Not to HIIT? International Journal of Sports Medicine. 2021;42(14):1319-1328. doi:10.1055/a-1481-8639
Schlagheck, M. L., Wucherer, A., Rademacher, A., Joisten, N., Proschinger, S., Walzik, D., Bloch, W., Kool, J., Gonzenbach, R., Bansi, J., & Zimmer, P. (2021). VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT or Not to HIIT? International Journal of Sports Medicine, 42(14), 1319–1328. https://doi.org/10.1055/a-1481-8639
@article{Schlagheck_Wucherer_Rademacher_Joisten_Proschinger_Walzik_Bloch_Kool_Gonzenbach_Bansi_et al._2021, title={VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT or Not to HIIT?}, volume={42}, DOI={10.1055/a-1481-8639}, number={14}, journal={International Journal of Sports Medicine}, publisher={Georg Thieme Verlag KG}, author={Schlagheck, Marit Lea and Wucherer, Anika and Rademacher, Annette and Joisten, Niklas and Proschinger, Sebastian and Walzik, David and Bloch, Wilhelm and Kool, Jan and Gonzenbach, Roman and Bansi, Jens and et al.}, year={2021}, pages={1319–1328} }
Schlagheck, Marit Lea, Anika Wucherer, Annette Rademacher, Niklas Joisten, Sebastian Proschinger, David Walzik, Wilhelm Bloch, et al. “VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT or Not to HIIT?” International Journal of Sports Medicine 42, no. 14 (2021): 1319–28. https://doi.org/10.1055/a-1481-8639.
M. L. Schlagheck et al., “VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT or Not to HIIT?,” International Journal of Sports Medicine, vol. 42, no. 14, pp. 1319–1328, 2021, doi: 10.1055/a-1481-8639.
Schlagheck, Marit Lea, et al. “VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT or Not to HIIT?” International Journal of Sports Medicine, vol. 42, no. 14, Georg Thieme Verlag KG, 2021, pp. 1319–28, doi:10.1055/a-1481-8639.

Export

Marked Publications

Open Data LibreCat

Search this title in

Google Scholar